Risk Factors Update Summary

• The company faces a potential loss of license rights if obligations under license agreements are not met.
• Potential impact of Preferred Warrants not exercised: up to $8 million gross proceeds lost.
• The expiration of key patents may lead to market entry of generic competitors.
• Series B-3 Preferred Stock conversion could require additional 11,309,019 shares reservation.
• The delay in commercializing the RhodoLED XL lamp due to supply chain issues.
• Dilution risk: Series B Convertible Preferred Stock conversion could substantially increase shares eligible for resale.
• A voluntary recall of Ameluz due to a manufacturing defect impacting product packaging.
• The company's ability to continue as a going concern due to operating losses and need for additional financing.
• The company's history of operating losses and accumulated deficit.
• The need for additional R&D expenditures to enhance product capabilities and develop new products.