Risk Factors Update Summary

• Implementation of changes to information technology systems may have significant impacts on manufacturing, sales, and finance functions.
• Introduction of weight loss drugs impacted da Vinci surgical system bariatric procedures, affecting revenue.
• Failure to attract and retain key personnel could harm the company's ability to compete.
• Addition of Beijing Surgerii Robotics Company Limited to list of competitor companies poses increased competition risk.
• Changes in labor relationships could materially impact the company's business, financial condition, and operations.
• Implementation of significant limits on hospital charges in certain provinces in China impacted procedures performed.
• Fluctuations in labor availability globally could affect the company's ability to attract and retain qualified personnel.
• Increased demand for materials led to global supply constraints and inflationary pressure in the supply chain.
• Changes in tax laws and effective tax rates may adversely affect the company's financial condition and results of operations.
• New product developments may negatively impact existing product demand and gross profit margins.
• Regulatory changes, such as the EU Medical Devices Regulation, could impact the company's ability to market products in the EU and EEA.
• Reliance on sole/singe-sourced suppliers poses risks of supply disruptions, affecting product demand and revenue.
• Stock price fluctuations may impact the company's financial performance and market perception.
• Cybersecurity risks heightened with increased sophistication of techniques, posing potential unauthorized access threats.