Risk Factors Update Summary

• Added the use of artificial intelligence technology to enhance operations and decision-making processes.
• Privacy laws may result in fines up to 5% of revenues in China, with fines ranging from RMB 50 million to 5% of revenues.
• Emphasized the importance of predicting and adapting to changing consumer preferences to avoid lower sales.
• Expanded on the risks associated with cybersecurity incidents, breaches, and cyberattacks, including ransomware.
• Addressed the evolving regulatory landscape concerning data privacy and protection laws.
• The company accrued a liability of approximately $3.3 billion for opioids-related claims.
• Highlighted the potential impact of fluctuations in currency exchange rates on financial performance.
• Noted the potential adverse effects of tax law changes and interpretations on financial performance.
• Mentioned the increased complexity of regulatory regimes related to data handling practices in various states.
• A quasi-judicial administrative process initiated against the Mexican subsidiary for alleged monopolistic practices.